diff --git a/tex/thesis.tex b/tex/thesis.tex index 2543d6c..64e5390 100644 --- a/tex/thesis.tex +++ b/tex/thesis.tex @@ -98,6 +98,8 @@ \newacronym{bcma}{BCMA}{B-cell maturation antigen} \newacronym{di}{DI}{deionized} \newacronym{moi}{MOI}{multiplicity of infection} +\newacronym{ifng}{IFN$\upgamma$}{interferon-$\upgamma$} +\newacronym{tnfa}{TNF$\upalpha$}{tumor necrosis factor-$\upalpha$} %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% % SI units for uber nerds @@ -1508,6 +1510,13 @@ cells, which was why the \ptmemp{} was so low compared to other data \label{fig:grex_results} \end{figure*} +We also quantified the cytokines released during the Grex expansion using +Luminex. We noted that in nearly all cases, the \gls{dms}-expanded T cells +released higher concentrations of cytokines compared to beads +(\cref{fig:grex_luminex}). This included higher concentrations of +pro-inflammatory cytokines such as GM-CSF, \gls{ifng}, and \gls{tnfa}. This +demonstrates that \gls{dms} could lead to more robust activation and fitness. + \begin{figure*}[ht!] \begingroup