From 40875b4efa2c95e5d829e95cdefe679398713b86 Mon Sep 17 00:00:00 2001 From: ndwarshuis Date: Fri, 30 Jul 2021 17:55:45 -0400 Subject: [PATCH] ADD diffusion figure to the kinetics stuff --- figures/dms_timing.svg | 1374 +++++++++++++++++++++++++++++++++++++++- tex/thesis.tex | 6 +- 2 files changed, 1356 insertions(+), 24 deletions(-) diff --git a/figures/dms_timing.svg b/figures/dms_timing.svg index 8567bde..7619555 100644 --- a/figures/dms_timing.svg +++ b/figures/dms_timing.svg @@ -74,6 +74,20 @@ d="m 24.34,23.47 h 83.57 v 84.44 H 24.34 Z" id="path15278" /> + + + + + + @@ -119,6 +133,736 @@ inkscape:label="Layer 1" inkscape:groupmode="layer" id="layer1"> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 0 + + + + + 10 + + + + + 20 + + + + + 30 + + + + + 40 + + + + + 50 + + + + + 60 + + + + + 70 + + + + + t (min) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 10 + + + + + 15 + + + + + 20 + + + + + 25 + + + + + 30 + + + + + 35 + + + + + 40 + + + + + concentration (ug/ml) + + + + + bulk concentration + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + exp1 + + + + + + + + exp2 + + + + + + + + ligand + + + + + + + + + + transform="matrix(1.3333333,0,0,-1.3333333,254.97336,164.53334)"> - a. b. c. + d. + transform="matrix(1.3333333,0,0,-1.3333333,9.200005,546.76003)"> d. + x="-0.8828125" + y="391.05334">e. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 0 + + + + + 2 + + + + + 4 + + + + + 6 + + + + + 8 + + + + + 10 + + + + + 12 + + + + + 14 + + + + + 16 + + + + + 18 + + + + + 20 + + + + + t (min) + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 2.4 + + + + + 2.6 + + + + + 2.8 + + + + + 3 + + + + + 3.2 + + + + + 3.4 + + + + + 3.6 + + + + + 3.8 + + + + + concentration (ug/ml) + + + + + bulk concentration + + + + + + + + + + + ligand + + + + + + + + + + diff --git a/tex/thesis.tex b/tex/thesis.tex index a581bbd..6b834bd 100644 --- a/tex/thesis.tex +++ b/tex/thesis.tex @@ -1325,6 +1325,7 @@ the \gls{mab} reaction should proceed in {\#}{mab curve}. % TODO add additional paragraph about how this diffusion coefficient was used to % estimate the wash step times. +% RESULT talk about the kinetic stuff in this figure more \begin{figure*}[ht!] \begingroup @@ -1332,6 +1333,7 @@ the \gls{mab} reaction should proceed in {\#}{mab curve}. \phantomsubcaption\label{fig:dms_biotin_rxn_mass} \phantomsubcaption\label{fig:dms_biotin_rxn_frac} \phantomsubcaption\label{fig:dms_stp_per_time} + \phantomsubcaption\label{fig:dms_mab_per_time} \phantomsubcaption\label{fig:dms_biotin_washed} \endgroup @@ -1339,7 +1341,9 @@ the \gls{mab} reaction should proceed in {\#}{mab curve}. {Reaction kinetics for microcarrier functionalization. \subcap{fig:dms_biotin_rxn_mass}{Biotin mass bound per time} \subcap{fig:dms_biotin_rxn_frac}{Fraction of input biotin bound per time} - \subcap{fig:dms_stp_per_time}{\Gls{stp} bound per time.} + \subcap{fig:dms_stp_per_time}{\Gls{stp} bound per time. Each dot is an + experimental run and the line is the fitted model.} + \subcap{fig:dms_mab_per_time}{Simulated \glspl{mab} bound per time.} \subcap{fig:dms_biotin_washed}{Biotin quantification via the \gls{haba} assay after washing.} }