diff --git a/tables/causal_inference_control.tex b/tables/causal_inference_control.tex index 717faca..16513ce 100644 --- a/tables/causal_inference_control.tex +++ b/tables/causal_inference_control.tex @@ -1,37 +1,39 @@ % Table created by stargazer v.5.2.2 by Marek Hlavac, Harvard University. E-mail: hlavac at fas.harvard.edu -% Date and time: Fri, Jul 23, 2021 - 12:30:10 PM +% Date and time: Fri, Aug 13, 2021 - 04:48:47 PM \begin{tabular}{@{\extracolsep{5pt}}lccc} \\[-1.8ex]\hline \hline \\[-1.8ex] % & \multicolumn{3}{c}{\textit{Dependent variable:}} \\ % \cline{2-4} \\[-1.8ex] & log(Fold Change) & \ptmemp{} & \dpthp{} \\ +% \\[-1.8ex] & (1) & (2) & (3)\\ \hline \\[-1.8ex] - Activation Method [DMS] & 0.890$^{***}$ & 0.027$^{**}$ & 0.089$^{***}$ \\ - Bioreactor [Grex] & $-$1.712$^{***}$ & $-$0.464$^{***}$ & 0.333$^{***}$ \\ - Feed Criteria [Glucose] & $-$0.143 & $-$0.017 & $-$0.001 \\ + Activation Method [DMS] & 0.836$^{***}$ & 0.035$^{***}$ & 0.074$^{***}$ \\ + Bioreactor [Grex] & $-$1.719$^{***}$ & $-$0.463$^{***}$ & 0.331$^{***}$ \\ + Feed Criteria [Glucose] & $-$0.148 & $-$0.016 & $-$0.002 \\ IL2 Feed Conc. [IU/ml] & $-$0.007$^{***}$ & 0.0002 & 0.001$^{***}$ \\ - CD19-CAR Transduced [True] & $-$1.015$^{***}$ & 0.585$^{***}$ & $-$0.171$^{***}$ \\ - Donor Age & 0.066$^{***}$ & $-$0.001 & $-$0.014$^{***}$ \\ - Donor BMI (kg/m2) & $-$0.265$^{***}$ & $-$0.045$^{***}$ & 0.070$^{***}$ \\ - Donor Gender & $-$2.213$^{***}$ & $-$0.190$^{***}$ & 0.391$^{***}$ \\ - Donor Demographic [Cauc.] & $-$1.325 & 0.498$^{***}$ & $-$0.289$^{***}$ \\ - Donor Demographic [Cauc./Pac. Isl.] & $-$4.154$^{***}$ & 0.646$^{***}$ & $-$0.251$^{**}$ \\ - Initial Cell Viability & $-$0.064$^{**}$ & $-$0.007$^{**}$ & 0.027$^{***}$ \\ - log(Initial CD4:CD8 Ratio) & $-$1.279$^{***}$ & 0.050 & 0.366$^{***}$ \\ - Media Age (days) & 0.0004 & $-$0.001$^{***}$ & 0.0002 \\ - Thaw Media Age (days) & $-$0.0005 & 0.001$^{***}$ & $-$0.0004$^{***}$ \\ - IL2 Reconstituted Age & $-$0.0001 & 0.00000 & 0.0002 \\ - Operator [2] & $-$0.651$^{***}$ & 0.044$^{*}$ & 0.034 \\ - Operator [3] & $-$0.343 & $-$0.201$^{***}$ & 0.180$^{***}$ \\ - Media Sampled [True] & $-$0.303 & $-$0.023 & 0.051 \\ - Constant & 18.988$^{***}$ & 1.765$^{***}$ & $-$4.737$^{***}$ \\ + CD19-CAR Transduced [True] & $-$1.038$^{***}$ & 0.589$^{***}$ & $-$0.178$^{***}$ \\ + Donor Age (years) & 0.066$^{***}$ & $-$0.001 & $-$0.014$^{***}$ \\ + Donor BMI (kg/m2) & $-$0.262$^{***}$ & $-$0.045$^{***}$ & 0.071$^{***}$ \\ + Donor Gender & $-$2.204$^{***}$ & $-$0.192$^{***}$ & 0.394$^{***}$ \\ + Donor Demographic [Cauc.] & $-$1.373$^{*}$ & 0.506$^{***}$ & $-$0.303$^{***}$ \\ + Donor Demographic [Cauc./Pac. Isl.] & $-$4.174$^{***}$ & 0.649$^{***}$ & $-$0.257$^{**}$ \\ + Initial Cell Viability & 1.355 & 0.408$^{***}$ & $-$0.716$^{***}$ \\ + log(Initial CD4:CD8 Ratio) & $-$0.064$^{**}$ & $-$0.007$^{**}$ & 0.027$^{***}$ \\ + Media Age (days) & $-$1.283$^{***}$ & 0.050 & 0.365$^{***}$ \\ + Thaw Media Age (days) & 0.0004 & $-$0.001$^{***}$ & 0.0002 \\ + IL2 Reconstituted Age & $-$0.0005 & 0.001$^{***}$ & $-$0.0004$^{***}$ \\ + Operator [2] & $-$0.0001 & 0.00000 & 0.0002$^{*}$ \\ + Operator [3] & $-$0.661$^{***}$ & 0.045$^{**}$ & 0.031 \\ + Media Sampled [True] & $-$0.317 & $-$0.205$^{***}$ & 0.188$^{***}$ \\ + luminex\_samples & $-$0.279 & $-$0.026 & 0.058 \\ + Constant & 19.077$^{***}$ & 1.751$^{***}$ & $-$4.712$^{***}$ \\ \hline \\[-1.8ex] -Observations & 162 & 162 & 162 \\ -R$^{2}$ & 0.764 & 0.872 & 0.864 \\ -Adjusted R$^{2}$ & 0.734 & 0.856 & 0.846 \\ -Residual Std. Error (df = 143) & 0.567 & 0.066 & 0.074 \\ -F Statistic (df = 18; 143) & 25.649$^{***}$ & 53.998$^{***}$ & 50.318$^{***}$ \\ +% Observations & 177 & 177 & 177 \\ +R$^{2}$ & 0.763 & 0.869 & 0.855 \\ +Adjusted R$^{2}$ & 0.735 & 0.853 & 0.837 \\ +% Residual Std. Error (df = 157) & 0.548 & 0.065 & 0.073 \\ +% F Statistic (df = 19; 157) & 26.660$^{***}$ & 54.664$^{***}$ & 48.594$^{***}$ \\ \hline \hline \\[-1.8ex] \textit{Note:} & \multicolumn{3}{r}{$^{*}$p$<$0.1; $^{**}$p$<$0.05; $^{***}$p$<$0.01} \\ diff --git a/tables/causal_inference_treat.tex b/tables/causal_inference_treat.tex index b2c34b0..38fde18 100644 --- a/tables/causal_inference_treat.tex +++ b/tables/causal_inference_treat.tex @@ -1,23 +1,23 @@ % Table created by stargazer v.5.2.2 by Marek Hlavac, Harvard University. E-mail: hlavac at fas.harvard.edu -% Date and time: Fri, Jul 23, 2021 - 12:30:08 PM +% Date and time: Fri, Aug 13, 2021 - 04:48:45 PM \begin{tabular}{@{\extracolsep{5pt}}lccc} \\[-1.8ex]\hline \hline \\[-1.8ex] - & \multicolumn{3}{c}{\textit{Dependent variable:}} \\ -\cline{2-4} +% & \multicolumn{3}{c}{\textit{Dependent variable:}} \\ +% \cline{2-4} \\[-1.8ex] & log(Fold Change) & \ptmemp{} & \dpthp{} \\ -\\[-1.8ex] & (1) & (2) & (3)\\ +% \\[-1.8ex] & (1) & (2) & (3)\\ \hline \\[-1.8ex] - Activation Method [DMS] & 0.903$^{***}$ & 0.048$^{*}$ & 0.011 \\ - Bioreactor [Grex] & $-$1.623$^{***}$ & $-$0.277$^{***}$ & 0.242$^{***}$ \\ - Constant & 2.555$^{***}$ & 0.309$^{***}$ & $-$0.378$^{***}$ \\ + Activation Method [DMS] & 0.840$^{***}$ & 0.060$^{***}$ & 0.007 \\ + Bioreactor [Grex] & $-$1.676$^{***}$ & $-$0.262$^{***}$ & 0.242$^{***}$ \\ + Constant & 2.640$^{***}$ & 0.288$^{***}$ & $-$0.376$^{***}$ \\ \hline \\[-1.8ex] -Observations & 162 & 162 & 162 \\ -R$^{2}$ & 0.440 & 0.317 & 0.177 \\ -Adjusted R$^{2}$ & 0.433 & 0.308 & 0.167 \\ -Residual Std. Error (df = 159) & 0.827 & 0.144 & 0.172 \\ -F Statistic (df = 2; 159) & 62.589$^{***}$ & 36.884$^{***}$ & 17.111$^{***}$ \\ +% Observations & 177 & 177 & 177 \\ +R$^{2}$ & 0.437 & 0.292 & 0.179 \\ +Adjusted R$^{2}$ & 0.431 & 0.284 & 0.169 \\ +% Residual Std. Error (df = 174) & 0.803 & 0.143 & 0.165 \\ +% F Statistic (df = 2; 174) & 67.576$^{***}$ & 35.945$^{***}$ & 18.937$^{***}$ \\ \hline \hline \\[-1.8ex] \textit{Note:} & \multicolumn{3}{r}{$^{*}$p$<$0.1; $^{**}$p$<$0.05; $^{***}$p$<$0.01} \\ -\end{tabular} \ No newline at end of file +\end{tabular} diff --git a/tex/thesis.tex b/tex/thesis.tex index 982a06d..f076c23 100644 --- a/tex/thesis.tex +++ b/tex/thesis.tex @@ -4666,6 +4666,8 @@ The code is available here: \url{https://github.gatech.edu/ndwarshuis3/mdma}. \newcommand{\ligs}{\textit{ligands}} \newcommand{\rcps}{\textit{receptors}} +% TODO make notation consistent + To model binding kinetics of either \gls{stp} or \glspl{mab} (here called \ligs{}), each microcarrier was assumed to be a porous sphere with a given number of binding sites for the \ligs{} (here called \rcps{}). The \rcp{}/\lig{}