diff --git a/figures/doe_responses.svg b/figures/doe_responses.svg
index 2434394..4ec5915 100644
--- a/figures/doe_responses.svg
+++ b/figures/doe_responses.svg
@@ -172,6 +172,244 @@
d="m 327,93.922 h 6 V 88 h -6 z"
id="path1554" />
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ transform="matrix(1.3333333,0,0,-1.3333333,11.776018,330.66133)">
a.
+ x="2"
+ y="14.101444">a.
b.
+ x="1.5078125"
+ y="179.76811">b.
+
+
+
+ Experiment
+
+
+
+
+
+
+
+
+ Initial DOEValidation DOE
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 1e+062e+063e+064e+06
+
+
+
+
+
+
+
+
+
+ 10203040
+ IL2 concentration(U/mL)
+ CD4+CCR7+CD62L+ cells
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 100020003000
+ DMS concentration(DMSs/mL)
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 60708090100
+ Functional mAbDensity (%)
+
+
+
+
+
+ Experiment
+
+
+
+
+
+
+
+
+ Initial DOEValidation DOE
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 0.10.20.30.40.5
+
+
+
+
+
+
+
+
+
+
+ 10203040
+ IL2 concentration(U/mL)
+ CD4:CD8 CD62L+CCR7+ Ratio
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 100020003000
+ DMS concentration(DMSs/mL)
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 60708090100
+ Functional mAbDensity (%)
+
+
+ c.
+ d.
diff --git a/tex/thesis.tex b/tex/thesis.tex
index feff183..49ff947 100644
--- a/tex/thesis.tex
+++ b/tex/thesis.tex
@@ -2269,36 +2269,40 @@ at \SI{10}{\IU\per\ml} throughout the remainder of this aim.
\includegraphics{../figures/doe_responses.png}
\phantomsubcaption\label{fig:doe_responses_mem}
\phantomsubcaption\label{fig:doe_responses_cd4}
+ \phantomsubcaption\label{fig:doe_responses_mem4}
+ \phantomsubcaption\label{fig:doe_responses_ratio}
\endgroup
\caption[T cell optimization through Design of Experiments]
{\gls{doe} methodology reveals optimal conditions for expanding T cell
subsets. Responses vs IL2 concentration, \gls{dms} concentration, and
functional \gls{mab} percentage are shown for
- \subcap{fig:doe_responses_mem}{total \ptmem{} T cells} and
- \subcap{fig:doe_responses_cd4}{total \pth{} T cells}. Each point represents
- one run.
+ \subcap{fig:doe_responses_mem}{total \ptmem{} T cells},
+ \subcap{fig:doe_responses_cd4}{total \pth{} T cells},
+ \subcap{fig:doe_responses_mem4}{total \ptmemh{} T cells}, and
+ \subcap{fig:doe_responses_ratio}{ratio of CD4 and CD8 T cells in the
+ \ptmem{} compartment}. Each point represents one run.
}
\label{fig:doe_responses}
\end{figure*}
-% \begin{table}[!h] \centering
-% \caption{Total CD62L+CCR7+ T cell response (first order regression)}
-% \label{tab:doe_mem1.tex}
-% \input{../tables/doe_mem1.tex}
-% \end{table}
+\begin{table}[!h] \centering
+ \caption{Total CD62L+CCR7+ T cell response (first order regression)}
+ \label{tab:doe_mem1.tex}
+ \input{../tables/doe_mem1.tex}
+\end{table}
-% \begin{table}[!h] \centering
-% \caption{Total CD62L+CCR7+ T cell response (third order regression)}
-% \label{tab:doe_mem2.tex}
-% \input{../tables/doe_mem2.tex}
-% \end{table}
+\begin{table}[!h] \centering
+ \caption{Total CD62L+CCR7+ T cell response (third order regression)}
+ \label{tab:doe_mem2.tex}
+ \input{../tables/doe_mem2.tex}
+\end{table}
-% \begin{table}[!h] \centering
-% \caption{Total CD4+ T cell response}
-% \label{tab:doe_cd4.tex}
-% \input{../tables/doe_cd4.tex}
-% \end{table}
+\begin{table}[!h] \centering
+ \caption{Total CD4+ T cell response}
+ \label{tab:doe_cd4.tex}
+ \input{../tables/doe_cd4.tex}
+\end{table}
\begin{table}[!h] \centering
\caption{Linear regression for total \ptmemh{} cells}