ENH integrate expansion figure
This commit is contained in:
parent
03907accdc
commit
8ea9b8f4ca
|
@ -123,6 +123,10 @@
|
||||||
\newcommand{\cdp}[1]{\pos{\cd{#1}}}
|
\newcommand{\cdp}[1]{\pos{\cd{#1}}}
|
||||||
\newcommand{\cdn}[1]{\cd{#1}-}
|
\newcommand{\cdn}[1]{\cd{#1}-}
|
||||||
\newcommand{\ptmem}{\cdp{62L}\pos{CCR7}}
|
\newcommand{\ptmem}{\cdp{62L}\pos{CCR7}}
|
||||||
|
\newcommand{\pth}{\cdp{4}}
|
||||||
|
\newcommand{\ptk}{\cdp{8}}
|
||||||
|
\newcommand{\ptmemh}{\pth\ptmem}
|
||||||
|
\newcommand{\ptmemk}{\ptk\ptmem}
|
||||||
|
|
||||||
\newcommand{\catnum}[2]{(#1, #2)}
|
\newcommand{\catnum}[2]{(#1, #2)}
|
||||||
\newcommand{\product}[3]{#1 \catnum{#2}{#3}}
|
\newcommand{\product}[3]{#1 \catnum{#2}{#3}}
|
||||||
|
@ -977,7 +981,7 @@ context of pure error). Statistical significance was evaluated at $\upalpha$ =
|
||||||
\phantomsubcaption\label{fig:dms_cells_fluor}
|
\phantomsubcaption\label{fig:dms_cells_fluor}
|
||||||
|
|
||||||
\endgroup
|
\endgroup
|
||||||
\caption[\gls{dms} Reaction timing]
|
\caption[T cells growing on \glspl{dms}]
|
||||||
{Cells grow in tight clusters in and around functionalized \gls{dms}.
|
{Cells grow in tight clusters in and around functionalized \gls{dms}.
|
||||||
\subcap{fig:dms_cells_phase}{Phase-contrast image of T cells growing on
|
\subcap{fig:dms_cells_phase}{Phase-contrast image of T cells growing on
|
||||||
\glspl{dms} on day 7}
|
\glspl{dms} on day 7}
|
||||||
|
@ -985,14 +989,41 @@ context of pure error). Statistical significance was evaluated at $\upalpha$ =
|
||||||
growing on \glspl{dms} on day 9. \Glspl{dms} were stained using
|
growing on \glspl{dms} on day 9. \Glspl{dms} were stained using
|
||||||
\gls{stppe} (red) and T cells were stained using \acd{45}-\gls{af647}.}
|
\gls{stppe} (red) and T cells were stained using \acd{45}-\gls{af647}.}
|
||||||
}
|
}
|
||||||
\label{fig:dms_flowchart}
|
\label{fig:dms_cells}
|
||||||
\end{figure*}
|
\end{figure*}
|
||||||
|
|
||||||
% 3-donor expansion figure
|
% 3-donor expansion figure
|
||||||
|
|
||||||
\subsection{DMSs lead to greater expansion and memory and CD4+ phenotypes}
|
\subsection{DMSs lead to greater expansion and memory and CD4+ phenotypes}
|
||||||
|
|
||||||
% phenotype expansion plots
|
% TODO add significance tests to this
|
||||||
|
\begin{figure*}[ht!]
|
||||||
|
\begingroup
|
||||||
|
|
||||||
|
\includegraphics{../figures/dms_vs_bead_expansion.png}
|
||||||
|
\phantomsubcaption\label{fig:dms_exp_fold_change}
|
||||||
|
\phantomsubcaption\label{fig:dms_exp_mem}
|
||||||
|
\phantomsubcaption\label{fig:dms_exp_cd4}
|
||||||
|
\phantomsubcaption\label{fig:dms_exp_mem4}
|
||||||
|
\phantomsubcaption\label{fig:dms_exp_mem8}
|
||||||
|
|
||||||
|
\endgroup
|
||||||
|
\caption[\gls{dms} vs bead expansion]
|
||||||
|
{\gls{dms} lead to superior expansion of T cells compared to beads across
|
||||||
|
multiple donors.
|
||||||
|
\subcap{fig:dms_exp_fold_change}{Longitudinal fold change of T cells grown
|
||||||
|
using either \glspl{dms} or beads. Significance was evaulated using t
|
||||||
|
tests at each timepoint}
|
||||||
|
Fold change of subpopulations expanded using either \gls{dms} or beads at
|
||||||
|
day 14, including
|
||||||
|
\subcap{fig:dms_exp_mem}{\ptmem{} cells},
|
||||||
|
\subcap{fig:dms_exp_cd4}{\pth{} cells},
|
||||||
|
\subcap{fig:dms_exp_mem4}{\ptmemh{} cells}, and
|
||||||
|
\subcap{fig:dms_exp_mem8}{\ptmemk{} cells}
|
||||||
|
}
|
||||||
|
\label{fig:dms_exp}
|
||||||
|
\end{figure*}
|
||||||
|
|
||||||
% phenotype flow plots
|
% phenotype flow plots
|
||||||
|
|
||||||
\subsection*{DMSs can be used to produce functional CAR T cells}
|
\subsection*{DMSs can be used to produce functional CAR T cells}
|
||||||
|
|
Loading…
Reference in New Issue